Founded in April, 2006, it is the first provincial college students' innovation and entrepreneurship center in Jiangsu. The center takes the same structure as that of SEUSP, with student innovation and entrepreneurship bases set in all of its branch parks, providing overall services for students’ innovation and entrepreneurship cultivation. 

Since its establishment, the center has turned out nearly 150 student enterprises, which have offered over 2000 jobs. Exemplary enterprises incubated here include Nanjing Tuniu Co., Ltd., Jiangsu Bangning Co., Ltd., Nanjing Sandemarion Co. Ltd and Nanjing Dsee Lab Digital Technology Co., Ltd.